Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes.

Jingjun ZhouBaiping CuiXiaochen WangHongkun WangJunnan ZhengFengfeng GuoYaxun SunHangping FanJiaxi ShenJun SuJue WangHaige ZhaoYiquan TangTingyu GongNing SunPing Liang

Published in: Stem cell research & therapy (2023)

signaling, metabolism, transcriptomic profile, cardiomyocyte structure and tissue engineering, thus providing more accurate cellular model for elucidating cellular and molecular mechanisms of cardiovascular diseases, screening drug-induced cardiotoxicity, and developing personalized and precision cardiovascular medicine.

Keyphrases

drug induced
tissue engineering
liver injury
high glucose
endothelial cells
cardiovascular disease
cell proliferation
induced pluripotent stem cells
adverse drug
single cell
high resolution
angiotensin ii
type diabetes
rna seq
transcription factor
mass spectrometry
cardiovascular risk factors