Intravenous administration of Penicillin results in therapeutic intravitreal levels in chronic postoperative endophthalmitis.
Chloe ThabetChloe C C GottliebBernard R HurleyGuijun ZhangAdeel SheraziJonathan B AngelPublished in: Journal of ophthalmic inflammation and infection (2021)
This study shows that intravenous Penicillin G administered every four-hours allows for adequate intravitreal concentrations of penicillin. Future studies are required to determine if the results of this study translate into improved clinical outcomes.