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A UV-induced self-reinforced hydrogel based on in situ hydrophobic aggregation of strained 1,2-dithiolane rings.

Yu JiangHuiqing ZhongQinwen TanDezhi ZhanAolin WangDaohong Zhang
Published in: Chemical communications (Cambridge, England) (2023)
A novel responsive hydrogel exhibiting self-reinforcement and self-healing capacity was developed based on the hydrophobic aggregation of strained 1,2-dithiolane rings. Oligomerization of 1,2-dithiolane within hydrophobic domains under UV irradiation not only reinforced the hydrogel but also maintained its dynamic cross-linked nature by converting the intraring dynamic S-S bond to an outer one.
Keyphrases
  • tissue engineering
  • aqueous solution
  • drug delivery
  • hyaluronic acid
  • ionic liquid
  • wound healing
  • cancer therapy
  • diabetic rats
  • drug induced
  • radiation therapy
  • oxidative stress
  • radiation induced
  • stress induced