Mobilization of the nonconjugative virulence plasmid from hypervirulent Klebsiella pneumoniae.
Yanping XuJianfeng ZhangMeng WangMeng LiuGuitian LiuHongping QuJialin LiuZixin DengJingyong SunHong-Yu OuJie-Ming QuPublished in: Genome medicine (2021)
The nonconjugative virulence plasmid in ST11 CRKP strains is putatively mobilized from hvKP or E. coli intermediates with the help of conjugative IncF plasmids. Our findings emphasize the importance of raising public awareness of the rapid dissemination of virulence plasmids and the consistent emergence of hypervirulent carbapenem-resistant K. pneumoniae (hv-CRKP) strains.