Off-label use of tacrolimus in children with Henoch-Schönlein purpura nephritis: a pilot study.

Dong-Feng ZhangGuo-Xiang HaoChun-Zhen LiYan-Jun YangFu-Juan LiuLing LiuXiao-Ying YuanRui-Hong LiLei DongQian DongEvelyne Jacqz-AigrainWei Zhao

Published in: Archives of disease in childhood (2018)

This pilot study showed that tacrolimus might be an effective and well-tolerated drug for the treatment of HSPN in children. CYP3A5 polymorphism had a significant impact on tacrolimus concentration.

Keyphrases

young adults
combination therapy