Characterization of gastrointestinal pathologies in the dystonia musculorum mouse model for hereditary sensory and autonomic neuropathy type VI.

Anisha Lynch-Godrei Yves De Repentigny Rebecca A Yaworski Sabrina Gagnon James ButcherJuliana ManoogianAlain Stintzi Rashmi Kothary

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

Dstdt-27J GI defects are not linked to ENS neurodegeneration, but are likely a result of an imbalance in autonomic control over the gut. Further characterization of HSAN-VI patient GI symptoms is necessary to determine potential treatments targeting symptom relief.

Keyphrases

mouse model
heart rate variability
heart rate
early onset
case report
deep brain stimulation
cancer therapy
physical activity
risk assessment
depressive symptoms
climate change
human health
patient reported