Inhibition of Niemann-Pick C1-Like 1 by Ezetimibe Reduces Dietary 5β,6β-Epoxycholesterol Absorption in Rats.
Bungo ShirouchiYumiko FurukawaYuri NakamuraAsuka KawauchiKatsumi ImaizumiHirosuke OkuBungo ShirouchiPublished in: Cardiovascular drugs and therapy (2019)
Our results indicate that ezetimibe-mediated inhibition of dietary OC absorption varies depending on the specific OC, and only the absorption of 5,6β-epoxy is significantly reduced.
Keyphrases