Initiation of Medical Therapy for Heart Failure Patients According to Kidney Function: A Danish Nationwide Study.

Deewa Zahir AnjumJarl Emanuel StrangeEmil FosbølCaroline Hartwell GarredMariam Elmegaard MalikCharlotte AnderssonPardeep S JhundJohn J V McMurrayMark C PetrieLars Valeur KøberMorten Schou

Published in: Clinical epidemiology (2023)

In a real-world HF cohort, patients with moderate and severe kidney dysfunction were associated with reduced use of MRA irrespective of age and frailty. Reduced use of RASi was associated with severe kidney dysfunction, whereas for patients with moderate kidney dysfunction, reduced use was mainly driven by aging and frailty. Reduced use of BB seemed to be primarily explained by aging and frailty.

Keyphrases

oxidative stress
high intensity
early onset
community dwelling
healthcare
heart failure
growth factor
magnetic resonance
drug induced
acute heart failure