Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases.

Mattia BellanFrancesco MuranoFederico CerutiCristina PiccininoStelvio TonelloRosalba MinisiniAilia GiubertoniDaniele SolaRoberta PedrazzoliVeronica MaglioneGiulia Francesca ManfrediAntonio AcquavivaRoberto PifferoGiuseppe PattiMario PirisiPier Paolo Sainaghi

Published in: Diagnostics (Basel, Switzerland) (2022)

ICOS and ICOS-L are increased in patients with PAH, irrespectively from the underlying cause, and represent promising candidate biomarkers for the diagnostic screening for PAH among CTDs patients.

Keyphrases

pulmonary arterial hypertension
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
pulmonary hypertension
pulmonary artery
patient reported outcomes