Trilaciclib dose selection: an integrated pharmacokinetic and pharmacodynamic analysis of preclinical data and Phase Ib/IIa studies in patients with extensive-stage small cell lung cancer.

Chao LiLowell HartTaofeek K OwonikokoRaid AljumailyCaio Max Rocha LimaPaul R ConklingRoy Timothy WebbRobert M JotteSteven SchusterWilliam J EdenfieldDeborah A SmithMark SalePatrick J RobertsRajesh K MalikJessica A Sorrentino

Published in: Cancer chemotherapy and pharmacology (2021)

NCT02243150; NCT02499770; NCT02514447.

Keyphrases

small cell lung cancer
electronic health record
big data
brain metastases
machine learning
bone marrow
deep learning
artificial intelligence