Chitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization.
Qi WangJiaxin DongMengxian DuXinna LiuShiqi ZhangDi ZhangWanyun QinXikun XuXianghui LiRuidong SuLeyi QiuBaoqiang LiHuiping YuanPublished in: International journal of nanomedicine (2024)
CRCD could serve as a potential novel treatment strategy for glaucoma, via incorporating RAPA into CDs, in turn not only mitigating its toxic side effects but also enhancing its therapeutic efficacy.
Keyphrases
- optic nerve
- cell death
- optical coherence tomography
- drug delivery
- inflammatory response
- signaling pathway
- endoplasmic reticulum stress
- oxidative stress
- lipopolysaccharide induced
- fluorescent probe
- sensitive detection
- combination therapy
- neuropathic pain
- human health
- risk assessment
- visible light
- replacement therapy
- smoking cessation
- genome wide analysis