Differences in cancer gene copy number alterations between Epstein-Barr virus-positive and Epstein-Barr virus-negative nasopharyngeal carcinoma.
Marc Lucas OoftJolique van IpenburgRob J M van de LooRick de JongCathy B MoelansRemco de BreeMartine J de HerdtSenada KoljenovićRob J Baatenburg de JongJ HardilloStefan Martin WillemsPublished in: Head & neck (2018)
The EBV-positive and EBV-negative NPC show some similarities in cancer gene CNAs suggesting a common pathogenic route but also important differences possibly indicating divergence in oncogenesis. Copy number gain/amplification of CCNL1 and PTK2 are possibly good predictors of survival in EBV-positive NPC.