CD163+ M2 Macrophages Promote Fibrosis in IgG4-Related Disease Via Toll-like Receptor 7/Interleukin-1 Receptor-Associated Kinase 4/NF-κB Signaling.
Akira ChinjuMasafumi MoriyamaNoriko Kakizoe-IshiguroHu ChenYuka MiyaharaA S M Rafiul HaqueKatsuhiro FurushoMizuki SakamotoKazuki KaiKotono KibeSachiko Hatakeyama-FurukawaMiho Ito-OhtaTakashi MaeharaSeiji NakamuraPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
CD163+ M2 macrophages promote fibrosis in IgG4-RD by increasing the production of fibrotic cytokines via TLR-7/IRAK4/NF-κB signaling.