Voltammetric sensing of dopamine based on a nanoneedle array consisting of NiCo2S4 hollow core-shells on a nickel foam.
Hongxiu DaiDuo ChenYuan LiPengfei CaoNan WangMeng LinPublished in: Mikrochimica acta (2018)
An array consisting of homogeneous NiCo2S4 hollow core-shell nanoneedles was fabricated and is shown to enable sensitive electrochemical determination of dopamine (DA). The array was grown directly on a nickel foam (NF) substrate by a two-step hydrothermal process. The hierarchical nanoarray consists of a homogeneous NiCo2S4 nanoneedle core and a NiCo2S4 nanosheet shell. A 3-dimensional micro/nano structure is formed due to the presence of the micropores of the NF. The electrode was characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. Compared to a plain NF electrode, the NiCo2S4-modified NF electrode displays higher electrocatalytic activity for the oxidation of DA by differential pulse voltammetry (DPV). The sensor, best operated at a typical working voltage of 134 mV (vs. saturated calomel electrode), has a linear response in the 0.5-100 μM DA concentration range and a 0.2 μM detection limit (at S/N = 3). The electrode is selective over ascorbic acid and uric acid. Graphical abstract Schematic presentation of an electrochemical sensor for selective determination of dopamine based on the use of a homogeneous NiCo2S4 hollow core-shell nanoneedle array on nickel foam.
Keyphrases
- electron microscopy
- molecularly imprinted
- uric acid
- carbon nanotubes
- signaling pathway
- high resolution
- metal organic framework
- lps induced
- solid phase extraction
- reduced graphene oxide
- high throughput
- pi k akt
- metabolic syndrome
- nuclear factor
- solid state
- oxidative stress
- gold nanoparticles
- inflammatory response
- label free
- mass spectrometry
- blood pressure
- case report
- immune response
- ionic liquid
- magnetic resonance
- oxide nanoparticles
- tandem mass spectrometry
- simultaneous determination
- nitric oxide
- electron transfer
- amino acid
- real time pcr
- liquid chromatography