Remote photoacoustic sensing using speckle-analysis.
Benjamin LengenfelderFanuel MehariMartin HohmannMarkus HeinleinErika ChelalesMaximilian J WaldnerFlorian KlämpflZeev ZalevskyMichael SchmidtPublished in: Scientific reports (2019)
Laser surgery is a rising surgical technique, which offers several advantages compared to the traditional scalpel. However, laser surgery lacks a contact-free feedback system which offers high imaging contrast to identify the tissue type ablated and also a high penetration depth. Photoacoustic imaging has the potential to fill this gap. Since photoacoustic detection is commonly contact based, a new non-interferometric detection technique based on speckle-analysis for remote detection is presented in this work. Phantom and ex-vivo experiments are carried out in transmission and reflection-mode for proof of concept. In summary, the potential of the remote speckle sensing technique for photoacoustic detection is demonstrated. In future, this technique might be applied for usage as a remote feedback system for laser surgery, which could help to broaden the applications of lasers as smart surgical tools.
Keyphrases
- minimally invasive
- loop mediated isothermal amplification
- coronary artery bypass
- fluorescence imaging
- real time pcr
- label free
- high resolution
- surgical site infection
- magnetic resonance
- risk assessment
- computed tomography
- atrial fibrillation
- human health
- current status
- percutaneous coronary intervention
- quantum dots
- contrast enhanced