Morning and evening salivary cortisol levels in patients with chronic widespread pain and those at high risk.

Nayab Begum Jason R TaylorChristopher BrownJonathan Rajan Brian G KeevilEmily PyeTimothy RaineyAnthony K P Jones

Published in: European journal of pain (London, England) (2021)

This study examines neurobiological changes in chronic widespread pain and high risk individuals. One strength of the study is the absence of centrally acting medication. We found high salivary cortisol common to Fibromyalgia and those at risk and identified contributing factors. Our results offer insight into the early mechanistic changes underlying Fibromyalgia development and open up possibilities for early diagnosis and prevention.

Keyphrases

chronic pain
pain management
neuropathic pain
emergency department
spinal cord injury
adverse drug
drug induced
postoperative pain