Dynamic contrast-enhanced magnetic resonance imaging in locally advanced rectal cancer: role of perfusion parameters in the assessment of response to treatment.
Maria CiolinaDamiano CarusoDomenico De SantisMarta ZerunianMarco RengoNorma AlfieriDaniela MusioFrancesca De FeliceAntonio CiardiVincenzo TomboliniAndrea LaghiPublished in: La Radiologia medica (2018)
Wash-out and Kep measured before CRT correlate with LARC grading. Ve changes during CRT, while Ktrans measured before CRT may predict the response to therapy. Therefore, DCE-MRI parameters can predict tumor aggressiveness and CRT efficacy, playing a role as imaging biomarkers in patients with LARC.
Keyphrases
- cardiac resynchronization therapy
- rectal cancer
- locally advanced
- contrast enhanced
- left ventricular
- squamous cell carcinoma
- neoadjuvant chemotherapy
- heart failure
- magnetic resonance imaging
- radiation therapy
- phase ii study
- high resolution
- clinical trial
- magnetic resonance
- photodynamic therapy
- replacement therapy
- combination therapy
- open label
- study protocol
- smoking cessation