Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats.
Kyle E ThomsonCameron S MetcalfThomas G NewellJennifer HuffSharon F EdwardsPeter J WestKaren S WilcoxPublished in: Epilepsia (2020)
Despite reductions in seizure burden, the lack of full seizure freedom for any ASD tested suggests that this screening paradigm may be useful for testing novel compounds with potential utility in pharmacoresistant epilepsy.