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Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes.

Mariana B AnguloAlexander BertalovitzMariana A ArgenzianoJiajia YangAarti PatelTheresa ZesiewiczThomas V McDonald
Published in: Molecular genetics & genomic medicine (2022)
These results offer novel insight into specific roles of frataxin deficiency pathogenesis in neurons and cardiomyocytes.
Keyphrases
  • gene expression
  • spinal cord
  • dna methylation
  • replacement therapy
  • high glucose
  • early onset
  • spinal cord injury
  • smoking cessation