Study on the Effect and Mechanism of Huaji Jianpi Decoction on Simple Obesity.

Mengmeng Zhu Baixia Zhang Jinghui Zhang Shaoqin Ge Meiyun Liu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

In this study, animal experiments, network pharmacology, and molecular biology were combined to establish a mouse model of simple obesity, confirm the role of HJJPD in the treatment of simple obesity, and preliminarily reveal the related mechanism. Relevant research results will provide a basis for the treatment of simple obesity and the drug discovery.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
type diabetes
high fat diet induced
weight gain
drug discovery
mouse model
adipose tissue
gene expression
skeletal muscle
dna methylation
single cell