Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease.
Andrew J AschenbrennerR Asaad BakshBessy BenejamJessica A Beresford-WebbAntonia CoppusJuan ForteaBenjamin L HandenSigan HartleyElizabeth HeadJudith JaegerJohannes LevinSandra V LoosliAnne-Sophie RebillatSilvia SaccoFrederick A SchmittKate E ThurlowShahid ZamanJason HassenstabAndre StrydomPublished in: Alzheimer's & dementia (Amsterdam, Netherlands) (2021)
We have identified a composite that is sensitive to early decline and thus may have utility as an outcome measure in trials to prevent or delay symptoms of AD in DS.