Isoflurane Anesthesia's Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model.
Yana Y ShpetkoIvan B FilippenkovAlina E DenisovaVasily V StavchanskyLeonid V GubskySvetlana A LimborskaLyudmila V DergunovaPublished in: Genes (2023)
We were able to determine the effects of the duration of anesthesia using isoflurane on the transcriptomes in the brains of rats at 24 h after tMCAO. Thus, specific genome responses may be useful in developing potential approaches to reduce damaged areas after cerebral ischemia and neuroprotection.