Heterogeneous burden of lung disease in smokers with borderline airflow obstruction.

Cheryl S PirozziTian GuPedro M QuibreraElizabeth E CarrettaMeiLan K HanSusan MurrayChristopher B CooperDonald P TashkinEric C KleerupIgor BarjaktarevicEric A HoffmanCarlos H MartinezStephanie A ChristensonNadia N HanselR Graham BarrEugene R BleeckerVictor E OrtegaFernando J MartinezRichard E KannerRobert Painenull null

Published in: Respiratory research (2018)

Ever-smokers with normal FEV1 and FEV1/FVC < 0.70 but > LLN are a heterogeneous group that includes significant numbers of individuals with and without radiographic evidence of smoking-related lung disease. These findings emphasize the limitations of diagnosing COPD based on spirometric criteria alone.

Keyphrases

smoking cessation
chronic obstructive pulmonary disease
lung function
risk factors
cystic fibrosis
drug induced