New approach to accurate interpretation of sickle cell disease newborn screening by applying multiple of median cutoffs and ratios.

Bichr AllafFranck PatinJacques ElionNathalie Couque

Published in: Pediatric blood & cancer (2018)

This new approach introduces tools for a quantitative interpretation in SCD NBS by HPLC methods and could allow standardization of interpretation between centers.

Keyphrases

sickle cell disease
ms ms
high resolution
simultaneous determination
mass spectrometry
high performance liquid chromatography
tandem mass spectrometry