The impact of a high-fat diet on physical activity and dopamine neurochemistry in the striatum is sex and strain dependent in C57BL/6J and DBA/2J mice.

Melissa S Totten Conner W WallaceDerek M PierceSteve C Fordahl Keith M Erikson

Published in: Nutritional neuroscience (2021)

Our study provides evidence for important sex and strain influences on the impact of a high-fat diet and obesity-induced behavior alterations and neurobiology dysregulation in the striatum.

Keyphrases

high fat diet
insulin resistance
high fat diet induced
adipose tissue
physical activity
metabolic syndrome
type diabetes
skeletal muscle
prefrontal cortex
body mass index
weight loss
uric acid
weight gain
drug induced