Untargeted and targeted gingival metabolome in rodents reveal metabolic links between high-fat diet-induced obesity and periodontitis.

Zi-Yun ChenTian-Tian XuZhao-Jia LiangLi ZhaoXiao-Qin XiongKun-Ke XieWan-Xin YuXiao-Wen ZengJie GaoYing-Hong ZhouGang LuoTing Yu

Published in: Journal of clinical periodontology (2021)

The obese population consuming excessive HFD display amplified metabolic response to periodontitis, presenting a metabolic susceptibility to exacerbated periodontal destruction.

Keyphrases

high fat diet induced
insulin resistance
metabolic syndrome
weight loss
adipose tissue
type diabetes
weight gain
high fat diet
mass spectrometry
single cell
bariatric surgery
case report
gene expression
physical activity
obese patients