Cost-effectiveness of routine screening for Lynch syndrome in colorectal cancer patients up to 70 years of age.

Celine H M Leenen Anne GoverdeEsther W de Bekker-GrobAnja WagnerMargot G F van LierManon C W SpaanderMarco J BrunoCarli M TopsAns M W van den OuwelandHendrikus J DubbinkErnst J KuipersWinand N M DinjensMonique E van LeerdamEwout W Steyerberg

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)

Routine LS screening by analysis of microsatellite instability, immunohistochemistry, and MLH1 hypermethylation in CRC patients ≤70 years of age is a cost-effective strategy with important clinical benefits for CRC patients and their relatives.Genet Med 18 10, 966-973.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
clinical practice
patient reported outcomes