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Usefulness of Cyclin D1/Podoplanin Dual Immunohistochemical Stain to Differentiate Malignant Mesothelioma From Reactive Mesothelial Proliferations.

Raghavendra PillappaAustin Blackburn WilesSadia SayeedValentina Robila
Published in: American journal of clinical pathology (2022)
The cyclin D1/podoplanin dual stain is reliable and may be used to aid in differentiation of benign mesothelial proliferations from malignant tumors. In addition, histologic features and other ancillary testing may support the classification of cases with an inconclusive cyclin D1/podoplanin staining.
Keyphrases
  • cell cycle
  • cell cycle arrest
  • machine learning
  • deep learning
  • cell proliferation
  • high glucose
  • cell death
  • endothelial cells