Quantitative cytomorphological comparison of SurePath and ThinPrep liquid-based cytology using high-grade urothelial carcinoma cells.

Chihiro OkudaAiko KyotakeAkihiro NakamuraTomoo ItohShingo Kamoshida Hiroyuki Ohsaki

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2021)

Our data indicated the reasonableness of using the N:C ratio as the major criterion for TPS on both SurePath and ThinPrep slides, and an N:C ratio cut-off of 0.7 as suitable for identifying HGUC cells. However, the severity of hyperchromasia and irregular nuclear borders differed between the processing methods.

Keyphrases

high grade
low grade
induced apoptosis
cell cycle arrest
electronic health record
high resolution
big data
cell death
deep learning