The genetic contribution to the comorbidity of depression and anxiety: a multi-site electronic health records study of almost 178 000 people.
Brandon J CoombesIsotta LandiKarmel W ChoiKritika SinghBrian FennessyGreg D JenkinsAnthony BatzlerRichard PendegraftNicolas A NunezY Nina GaoEuijung RyuPriya WickramaratneMyrna M Weissmannull nullJyotishman PathakJ John MannJordan W SmollerLea K DavisMark OlfsonAlexander W CharneyJoanna M BiernackaPublished in: Psychological medicine (2023)
This study suggests that depression and anxiety have partially independent genetic liabilities and the genetic vulnerabilities to depression and anxiety make distinct contributions to comorbid depression and anxiety.