Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion.

Kimberly E InmanCarlo Donato CaiaffaKristin R MeltonLisa L SandellAnnita AchilleosTsutomu KumePaul A Trainor

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

Our data indicate Foxc2 is required for proper migration of cardiac neural crest cells, septation of the outflow tract, and development of the ventricles. Developmental Dynamics 247:1286-1296, 2018. © 2018 Wiley Periodicals, Inc.

Keyphrases

cell migration
induced apoptosis
left ventricular
cell cycle arrest
mitral valve
pulmonary hypertension
electronic health record
pulmonary artery
oxidative stress
endoplasmic reticulum stress
cell death
cell proliferation
machine learning
congenital heart disease
data analysis