Anti-Inflammatory Effect for Atherosclerosis Progression by Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitor in a Normoglycemic Rabbit Model.
Seul Gee LeeByeong-Keuk KimJung Jae LeeJung-Sun KimOh-Hyun LeeChoong Ki KimDarea KimEun Young LeeJaewon OhSeil ParkOk Hee JeonSung Jin HongChul-Min AhnByeong-Keuk KimYoung-Guk KoDoonghoon ChoiMeyong-Ki HongYang Soo JangPublished in: Korean circulation journal (2020)
These results together suggest that SGLT-2 inhibitor exerts an anti-atherosclerotic effect through favorable modulation of inflammatory response as well as macrophage characteristics in non-diabetic situation.