Pharmacokinetics and clinical efficacy of acetaminophen (paracetamol) in adult horses with mechanically induced lameness.
Melissa A MercerHarold C McKenzieChristopher R ByronRobert S PleasantSophie H BogersRoberto M Council-TrocheStephen R WerreTravis BurnsJennifer L DavisPublished in: Equine veterinary journal (2022)
Acetaminophen at 30 mg/kg produced a more rapid improvement in lameness scores and heart rate compared with other treatments in this model. Further evaluation of the pharmacokinetics and safety of repeated oral dosing of acetaminophen at 30 mg/kg is needed to determine clinical utility.