Sepsis with liver dysfunction and coagulopathy predicts an inflammatory pattern of macrophage activation.

Renee R AnderkoHernando GómezScott W CannaBita ShakooryDerek C AngusDonald M YealyDavid T HuangJohn A KellumJoseph A Carcillonull null

Published in: Intensive care medicine experimental (2022)

The HBD + DIC phenotype identified patients with high mortality and a molecular signature resembling that of MAS. These observations suggest trials of MAS-directed therapies are warranted.

Keyphrases

oxidative stress
cardiovascular events
acute kidney injury
intensive care unit
septic shock
adipose tissue
risk factors
single molecule
type diabetes