Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Yuanjiao ZhangXichao YuRongze SunJie MinXiaozhu TangZigen LinSiyuan XieXinying LiShengfeng LuZhidan TianChunyan GuLesheng TengYe YangPublished in: Clinical and translational medicine (2022)
Our findings demonstrate that targeting the SFRS8/CACYBP/β-catenin axis may be a promising strategy for MM diagnosis and treatment.