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Multiple primary malignances managed with surgical excision: a case report with next generation sequencing analysis.

Chiara RomanoSandra Di GregorioMaria Stella PennisiElena TirròGiuseppe BroggiRosario CaltabianoLivia ManzellaMartino RuggieriPaolo VigneriAntonio Di Cataldo
Published in: Molecular biology reports (2022)
In summary, NGS analysis contributed to defined different molecular profiles for two tumors developed in the span of two years, thus allowing diagnosing the case as MPN. However, NGS was unable to establish a direct correlation between the identified alterations and cancer development.
Keyphrases
  • gene expression
  • copy number
  • young adults
  • dna methylation