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The Diagnostic Accuracy of Serum Alpha-Fetoprotein Levels in Follow-up for Recurrence of Sacrococcygeal Teratoma; a Nationwide Review of SCT Cases in the Netherlands.

Lieke J van HeurnMarijke E B KremerIvo de BlaauwRobertine van BarenWim G van GemertJohannes B van GoudoeverCornelius E J SlootsMarieke J WitvlietL W Ernest van HeurnJoep P M Derikx
Published in: Journal of pediatric surgery (2024)
Dynamics of serum AFP levels are not different between patients with and without recurrence after initial resection of SCT. Serum AFP levels are not predictive for mature or immature recurrent SCT and normal AFP levels do not rule out recurrent SCT. However, serum AFP levels exceeding 55 μg/L can indicate recurrent SCT, especially malignant recurrences.
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