CTC-177, a novel drug-Fc conjugate, shows promise as an immunoprophylactic agent against multidrug-resistant Gram-negative bacterial infections.
Arianne LoveyAnnie LeeAllison YuMila KrelMingming WangPadmaja PaderuThomas BradyGrayson HoughQiping ZhaoJames M BalkovecDavid S PerlinYanan ZhaoPublished in: JAC-antimicrobial resistance (2024)
These data support the continued development of Cloudbreak™ DFCs as broad-spectrum prophylactic agents against Gram-negative infections.