A versatile enrichment of functionalized calixarene as a facile sensor for amino acids.
Jaymin ParikhKeyur D BhattKrunal ModiNihal PatelAjay DesaiSandeep KumarBrij MohanPublished in: Luminescence : the journal of biological and chemical luminescence (2022)
Amino acids are the most important part of the human biological system due to their role in living processes. The role of amino acids stretches beyond their traditional role as a building block for proteins, and deficiency of amino acids could lead to decreased immunity, digestive problems, depression, fertility issues, lower mental alertness, slowed growth in children, and many other health issues. The acute detection of amino acids is necessary to determine the human health domain. Here, in this review, we summarize and study the calixarenes as complexes that are of immeasurable value and their utilization for amino acid detection. Key factors such as noncovalent forces, limit of detection, and the supramolecular chemistry of calixarenes with amino acids have been well described. This study presents the most recent efforts made towards the development of potential and highly efficient calixarene-based sensors for the detection of amino acids.
Keyphrases
- amino acid
- human health
- highly efficient
- mental health
- risk assessment
- label free
- healthcare
- endothelial cells
- public health
- young adults
- intensive care unit
- quantum dots
- gold nanoparticles
- physical activity
- mass spectrometry
- high resolution
- health information
- induced pluripotent stem cells
- liquid chromatography
- health promotion
- replacement therapy