Exosomal miR-155-5p drives widespread macrophage M1 polarization in hypervirulent Klebsiella pneumoniae-induced acute lung injury via the MSK1/p38-MAPK axis.

Yihan XuChunying ZhangDanni CaiRongping ZhuYingping Cao

Published in: Cellular & molecular biology letters (2023)

The aforementioned results indicate that exosomal miR-155-5p drives widespread macrophage inflammation and M1 polarization in hvKp-induced ALI through the MSK1/p38-MAPK Axis.

Keyphrases

klebsiella pneumoniae
high glucose
diabetic rats
multidrug resistant
escherichia coli
oxidative stress
adipose tissue
endothelial cells
lps induced