Immunoliposomes for detection of rupture-prone intracranial aneurysms.
Behnam Rezai JahromiVladimir ZamotinChristian CodeEliisa NettiMartina B LoreyKari AlitaloKatariina ÖörniAki LaaksoRiikka TulamoMika NiemeläPublished in: Acta neurochirurgica (2023)
Our work opens a new avenue for using contrast labeled immunoliposomes for detecting rupture-prone aneurysms. Immunoliposomes can cary gadolinium and selectively bind to inflammatory section of aneurysm that can be detected with MRI. Further research is needed to develop immunoliposomes to be used with MRI in humans to target treatment to those patients who benefit from it the most.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- magnetic resonance
- diffusion weighted imaging
- computed tomography
- coronary artery
- oxidative stress
- pet imaging
- combination therapy
- loop mediated isothermal amplification
- label free
- abdominal aortic aneurysm
- replacement therapy
- positron emission tomography
- pet ct
- quantum dots