Inhibition of tartrate-resistant acid phosphatase 5 can prevent cardiac fibrosis after myocardial infarction.
Shujun YangLiying PeiZijie HuangYinsheng ZhongJun LiYinghui HongHuibao LongXuxiang ChenChangqing ZhouGuanghui ZhengChaotao ZengHaidong WuTong WangPublished in: Molecular medicine (Cambridge, Mass.) (2024)
ACP5 may influence the proliferation, migration, and phenotypic transition of CFs, leading to the development of myocardial fibrosis after MI through modulating the ERK/GSK3β/β-catenin signaling pathway.