A computational diffusion model to study antibody transport within reconstructed tumor microenvironments.

Ana Luísa CartaxoJaime AlmeidaEmilio J GualdaMaria MarsalPablo Loza-AlvarezCatarina BritoInês A Isidro

Published in: BMC bioinformatics (2020)

We present a computational and microscopy framework to track and simulate antibody transport within the tumor microenvironment that complements the previously established in vitro models platform. This framework paves the way to the development of a valuable tool to study the influence of different components of the tumor microenvironment on antibody transport.

Keyphrases

high throughput
high resolution
single molecule
high speed