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The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition.

Michael Dominic SaccoYanmei HuMaura Verenice GongoraFlora MeilleurMichael Trent KempXiujun ZhangJun WangYu Chen
Published in: Cell research (2022)
Keyphrases
  • small molecule
  • sars cov
  • protein protein
  • respiratory syndrome coronavirus
  • adverse drug
  • drug induced
  • coronavirus disease
  • electronic health record