A study of Drynaria fortunei in modulation of BMP–2 signalling by bone tissue engineering

Guo-Chung Dong Tzn-Yuan Ma Chi-Han Li Chih-Ying Chi Chao-Ming Su Chih-Ling Huang Yan-Hsiung Wang Tzer-Ming Lee

Published in: Turkish journal of medical sciences (2020)

GSB and its marker compound (naringin) could inhibit the binding of BMP-2 and BMPR-1A to control cell differentiation by blocked BMPR-1A signalling and enhanced BMPR-1B signalling. GSB and naringin could be good natural BMP regulators for bone tissue engineering.

Keyphrases

tissue engineering
bone regeneration
pulmonary arterial hypertension
mesenchymal stem cells
bone mineral density
soft tissue
bone loss
pulmonary hypertension
transcription factor
postmenopausal women
binding protein
dna binding