Drug Safety Signal Detection in a Regional Healthcare Database Using the Tree-Based Scan Statistic and Comparison to Three Other Mining Methods.

Hailong LiZhao HouyuLin HongboShen PengZhan Siyan

Published in: British journal of clinical pharmacology (2023)

TreeScan outperformed the crude cohort, BCPNN, and GPS in detecting statin-related AEs in an electronic healthcare database. Therefore, it can be used as a complementary tool for other signal detection methods in drug safety surveillance.

Keyphrases

healthcare
adverse drug
loop mediated isothermal amplification
label free
real time pcr
public health
computed tomography
cardiovascular disease
coronary artery disease
type diabetes
drug induced
magnetic resonance
emergency department
quantum dots