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Optimal timing of antiretroviral therapy initiation in children and adolescents with HIV-associated pulmonary tuberculosis.

Alexander W KayJose Mendez ReyesTara DevezinMeenakshi BakayaTeresa SteffySandile DlaminiAmos MsekandianaTara NessJason BachaPauline AmugeMogomotsi MatshabaMoses ChodotaPhoebe NyasuluLineo ThahaneLumumbwa MwitaAdeodata KekitiinwaAndrew DiNardoBhekumusa LukheleLes KirchnerAnna Mandalakas
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
This retrospective study demonstrated no increase in mortality among CALHIV initiating ART less than two-weeks from TB treatment initiation. Given the broad health benefits of ART, this evidence supports the recent WHO recommendation for CALHIV to initiate ART within two-weeks of initiating TB treatment.
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