Multiplex PCR Unyvero i60 ITI application improves detection of low-virulent microorganisms in periprosthetic joint infections.

Irene Katharina SigmundReinhard WindhagerFlorian SeveldaKevin StaatsStephan Engelbert PuchnerSandra StenickaFlorian ThalhammerJohannes Holinka

Published in: International orthopaedics (2018)

With a moderate agreement between synovial fluid mPCR and culture, the mPCR system could be a useful adjunct in diagnosing a PJI pre-operatively. Due to faster availability of results and a higher detection rate of low-virulent microorganisms, it can complement conventional culture.

Keyphrases

real time pcr
loop mediated isothermal amplification
label free
high throughput
high intensity
total hip
total knee arthroplasty
disease virus