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Antipsychotics and risk of QT prolongation: a pharmacovigilance study.

Constance BordetPhilippe GarciaFrancesco SalvoAnthony TouafchiaMichel GalinierAgnès SommetFrançois Montastruc
Published in: Psychopharmacology (2022)
This large study in a real-world setting suggests that sertindole and ziprasidone were the antipsychotics drugs associated with the highest risk of QT prolongation reporting. Our results suggest that lurasidone is less associated with QT interval prolongation reports. Our study also suggests that antipsychotics with the higher hERG affinity are more associated with to QT prolongations reports.
Keyphrases
  • drug induced
  • adverse drug