Sexual behavior and testis morphology in the BACHD rat model.

Arianna NovatiLibo Yu-TaegerIrene Gonzalez MenendezLeticia Quintanilla MartinezHoa Huu Phuc Nguyen

Published in: PloS one (2018)

The testis phenotype in the BACHD rat model does not mimic the changes observed in human HD testis. The altered sexual behavior in BACHD rats at three months of age could be to a certain extent representative of and share common underlying pathways with some of the sexual disturbances in HD patients. Further investigating the biological causes of the sexual phenotype in BACHD rats may therefore contribute to clarifying the mechanisms at the base of sexual behavior changes in HD.

Keyphrases

mental health
end stage renal disease
endothelial cells
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors